Taking a Devil deal breaks the cross and prevents the damage up next floor, Taking free pickups such as Black hearts in the Devil room also count, UNLOCK: Unlock this item by defeating The Beast as Judas, When you die, you turn into a ghost with 1/2 a red heart and flying, that is chained to your body for 10 seconds. Brimstone - No effect. Haemolacria's appearance prior to Booster Pack #5. *, bag, grey, cry, blue, tear, shia paper bag sackhead, sad, Gives Isaac a cone of light infront of him that slows any enemies inside it and their tears, The light faces the direction that you are facing, not the direction you are firing, Removes Curse of Darkness for the current floor, if picked up on a floor where the curse is active, * Shop, Greed Mode Item Room, white, blue, inhaler, A purple familiar fly that follows your exact movement on a 1 second delay and deals 2 contact damage to enemies, When used, places an explosive TNT barrel next to you, The TNT barrel can be pushed and used to explode rocks or damage enemies, If used a second time in the same room while the last TNT barrel is still there, it will remotely explode the first TNT and not spawn another, REPENTANCE - Added to the Gold Chest Pool. When used, it retrieves the Forgotten skull, causing it to shoot back into your arms, Tainted Bethany - Spawns four random item wisps of high quality with significantly higher HP than normal, Tainted Jacob - Dark Esau splits into 2. This does not work with items that grant a charged attack but also override Technology's costume, e.g. The finger deals 10% of your normal damage to all enemies in the same direction that the finger is pointing, The finger will also deal damage to entities such as fires and poops, Applies on-hit status effects such as the burning debuff from Fire Mind, Spawns guppy flies if you have the Guppy transformation, Isaac gains a shadow familiar that will follow Isaac's movement pattern delayed by 1 second and deal 5 contact damage to enemies per tick, Shade is absorbed by Isaac after dealing 666 damage. 3c pickups become 2c, Taking more than 1 steam sale reduces the price of all items even further, This item is called Steamy Sale on PS4, PS Vita, Xbox One and Switch versions, probably due to copyright reasons, Item Pool: Shop, Greed Miniboss, Shopkeeper, * shop room pool, shop item pool, red, pink, white, paper, Spawns 6 troll bombs at random locations around the room, Bombs are effected by other passive bomb items, Has a chance to drop from the Pride miniboss fight, Item Pool: Item Room, Library, Pride Miniboss, * Anarchist's Cookbook, Anarchists Cookbook library pool, library room, book room pool, item room, treasure room, item room pool, Using this card will also open a pathway of red rooms back to the regular floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Jacob, "May the darkness swallow all around you", When used, grants +1.5 Damage Up, turns your hearts to Bone hearts and the Spirit of the Night effect (Spectral tears and the ability to fly) for the current floor, Also gives the Curse of Darkness effect that can't be removed for the current floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Lazarus, Creates a trapdoor to a guaranteed crawl space, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Eden, When used, this copies the effect of the card, pill, rune, soul stone or active item you used most recently, UNLOCK: Unlock this card by defeating Mega Satan as Tainted Eden, Turns all pedestal items in the current room into rotating items, which cycle between the old item and a random new item every second, This allows you to effectively reroll items like with The D6, but choose the old item as well if you want, Tainted Isaac has this effect passively for all items, If you use more than one in the same room, each pedestal item will cycle through +1 random item, Items are chosen from the item pool related to the current item, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Isaac, When used, all enemies in the current room drop half a red heart that will disappear after 2 seconds if not picked up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Magdalene, When used, this Soul Stone creates Red rooms for every possible exit in the current room, Red outlines of doors appear where this Soul Stone will create exits for, See the Red Key item description for more information about these Red rooms behave, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Cain, Activates the Dark Arts item effect, which turns Isaac into a ghost for a few seconds. Transformations shop item pool, x, paper, Makes all of Isaac's familiars stronger and bigger, Causes most familiars to deal double damage, Has no effect on most familiars that scale with Isaac's tear damage, * key master pool, key beggar pool, key judgement pool, shop room pool, shop item pool, red, heart, This can be anything that would normally drop from a chest including pedestal items, When used, this item causes Isaac to become humongous for 30 seconds, While huge, Isaac is invincible and can crush objects, doors and enemies, For the duration of the effect this gives you a x4 Damage Multiplier and +2.0 Range Up, but your rate of fire goes way down. Shows you to see the contents of chests, sacks, shopkeepers and items that will drop from fires before you destroy them, Doesn't work on tinted rocks and other obstacles (e.g. the lost item pool, white, black, Each time you take damage, you gain a damage up which lasts for the rest of the floor and turn a darker red colour each time, After taking 6 hits Bloody Lust doesn't give you any further damage increases, Damage given for each hit increases as follows: +0.5, +0.7, +0.9, +1.1, +1.3, +1.5, REPENTANCE - The damage increments have changed slightly, UNLOCK: Unlock this item by beating the Isaac boss with Samson, * item room, treasure room, item room pool, the lost item pool, starting, red, blood, drop, Upon use, reveals the map and drops either a soul heart or a random card/rune (50% chance for each), It reveals the location of the secret room, however it doesn't reveal the Super secret room, Has a chance to drop from playing a fortune machine. Generally every interaction and synergy that applies to Chemical Peel also . Curses Tears are fired in an arc. If there are no enemies this pill spawns 1-3 blue spiders instead, One makes you smaller - Reduces Isaac's size and hitbox size, One makes you larger - Increases Isaac's size, but does not affect the size of his hitbox, Percs - Causes Isaac to only take half a heart of damage from all sources for the current room (The Wafer effect). the ability to fly. From the Sacred Heart to the Magic Mushroom and the mighty Brimstone, here are some of the best and strongest items available in The Binding Of Isaac. Pickup Quote "This could be a sign of a superficial or small blood . ), Prevents your stats from being reduced any more for the rest of the run, e.g. The damage bonus is unaffected by both positive and negative damage multipliers. See the Broken Shovel / Mom's Shovel items for more information on how to unlock, Rotten Hearts fill up a whole container the same as normal red hearts, or the rightmost heart if you're at full health, Every time you clear a room, you'll spawn 2 Blue Flies for each Rotten Heart you currently have, UNLOCK: Unlock this by entering the Corpse floor for the first time, Spawns 2-3 pills, black/bone hearts and/or bombs when picked up, Can spawn in place of a regular sack, including in Shops for 7c, Only one heart can spawn per sack as a maximum, UNLOCK: Unlock this by defeating Mega Satan as Tainted Judas, 48 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups. purple, pink, mask, face, Puts a shield in front of Isaac which blocks projectiles, The shield will rotate based on the direction in which Isaac is firing tears, * angel room pool, god room pool, angel room item, blue, silver, metal, Gives Isaac a laser that will fire at random intervals in addition to your normal tears, Each laser does damage equal to your current tear damage, The laser will occasionally fire with one of these effects: Hook Worm, Spoon Bender, Tiny Planet, Mysterious Liquid, Rubber Cement, Luck has no effect on the rate at which Tech.5 fires and does not scale with items that increase your tears stat, UNLOCK: Unlock this item by beating Challenge #18 (The Host), * technology.5, tech 5, item room, treasure room, item room pool, white, red, eye, robot, Isaac now shoots two tears at once, but dealing -20% damage each, Unlike the Inner Eye and Mutant Spider items, this double shot item does not give a tears down, * 20 20, 2020, item room, treasure room, item room pool, black glasses, spectacles, Reveals the locations of the secret and super secret room for the current floor and all future floors, UNLOCK: Unlock this item by donating 10 pennies to the Shop, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, Binding of Isaac: Rebirth Wiki is a FANDOM Games Community. The signals tell your spleen to release . the lost item pool, gold, orange, yellow, cross, pope, hat, A familiar the follows Isaac and fires random tears, Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc, * item room, treasure room, item room pool, purple, Upon use, opens all closed doors in the current room, including the ones which require a key to enter and secret room doors, Can be used to open the golden door that appears in the Dark Room or the Chest, Cannot be used to escape the Mom's Foot boss, open angel/devil rooms, or open the door to the Blue Womb floor, UNLOCK: Unlock this item by collecting both Key Pieces #1 & #2 for the first time, * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, I was incorrect. A member of the Tulsa-based pop group Hanson said he feels a duty to share his "scary experience" with deep vein thrombosis while health officials in his home state work to promote awareness of the medical condition. https://bindingofisaacrebirth.fandom.com/wiki/File:Technology_shot.wav, https://bindingofisaacrebirth.fandom.com/wiki/File:Technology_shot_weak.wav, https://bindingofisaacrebirth.fandom.com/wiki/File:Technology_shot_strong.wav, https://bindingofisaacrebirth.fandom.com/wiki/File:Technology_shot_burst.wav, Replaces tears with a laser beam with unlimited range and. Lil Clot is an unlockable trinket added in The Binding of Isaac: Repentance. when entering the item room, Gives +1 Soul Heart when starting each new floor after picking this up, Currently this effect doesn't work in Greed Mode - It will show 2 items but the item rooms will have different items in them, Gives +0.4 Tears Up for each room completed without taking damage, up to a maximum of +2.0 Tears Up, When you take damage, the tears bonus is reset, Picking this item up counts and gives you a temporary +0.4 Tears Up as well, Allows you to double-tap the shoot button to create a holy shield for 1 second that pushes enemies back and deals 10 damage to them if they touch it, The shield also reflects enemy shots and beams back at them for some extra damage, Can only be activated every 3 seconds (Shown by a white glow and a ticking noise). REPENTANCE - Bombs no longer knock each other around when the player has Fast Bombs, allowing for a more controlled line of explosions. Item pedestals will cycle between two different items, allowing players to pick the one they want. in The Chest as Apollyon, Upon entering a room with enemies, spawns a Black Locust that deals quadruple Isaac's damage, applied as two hits of double damage, UNLOCK: Unlock this trinket by defeating The Lamb as Apollyon, At the start of each new hostile room you spawn 2-5 white attack flies, which will target a nearby enemy and deal double your tear damage to it, UNLOCK: Unlock this trinket by defeating Boss Rush as Apollyon, When killing an enemy, you have a very small chance to gain the ability to fly for the rest of the room, UNLOCK: Unlock this trinket by defeating Greedier Mode with Azazel, Stem Cell heals Isaac's red heart containers to 50% each floor, If Isaac already has 50% health or more, it heals half of a heart instead, UNLOCK: Unlock this trinket by defeating Greedier Mode with Samson, Fully recharges your active item at the start of each boss fight, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Zaratus, Gives you the Holy Mantle shield effect at the start of every new floor, which protects you from the next hit of damage you take, Does not recharge until the start of the next floor, Stacks with the effects from Holy Mantle and Blanket, but it does not stack with Holy Card, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ep and Mills, Using your active item while holding this trinket will drop it back on a pedestal on the ground, Also after taking damage, you have a very small chance to drop one of your passive items, One-time use active items will be consumed and not dropped, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by MarkusLeben and iguesti, *, yellow, golden, box, block, square, cube, Holding this trinket will cause the Angel mini bosses to drop normal items instead of Key Pieces, Added as part of the Afterbirth+ Booster Pack #2, designed by Edmund McMillen, While held, the last door Isaac went through stays open, allowing him to leave the room even if enemies are in it, This trinket works on boss rooms (except Ultra Greed) and devil rooms containing Krampus, allowing you to exit out mid-fight, UNLOCK: Unlock this trinket by blowing up doors and secret room walls 50 times, *, door, stop, wedge, cheese, wood, brown, hodor, game of thrones, Wylis, After being picked up, a yellow laser chain now flows through Isaac's familiars, Added as part of the Afterbirth+ Booster Pack #4 and based on the Steam Workshop mod created by Strawrat and Aczom, While held, spawns +1 friendly blue fly every time you pick up a coin, Added as part of the Afterbirth+ Booster Pack #5. It can only be fired after a short charge-up period (approximately 1-2 seconds until Isaac's head begins flashing red). Blood clotting becomes a problem when it blocks your blood . UNLOCK: Unlock this item by defeating Ultra Greed as Apollyon, At the start of each new hostile room, you have a 20% chance to gain a random charmed familiar which will fight for you, The charmed enemy has its own health bar and will die if it takes enough damage, Charmed enemies persist between each room and floor for as long as they stay alive, Allows you to have more than one charmed familiar at a time if you can keep them alive, * pokemon, phone, black, green, blue, gps, Every time one of your tears hits an enemy, it has a chance to start bleeding, which will cause it to take damage every 5 seconds, The bleed damage dealt by BackStabber is based on how quickly an enemy is moving (faster enemies take more damage), Damaging enemies from behind gives the bleed effect a 100% chance to apply, While an enemy bleeds, they leave behind creep that damages other enemies, The tear that inflicts the bleed effect also deals double damage, *, knife, dagger, red, heart, silver, knife, When used, Sharp Straw will deal damage to all enemies in the room, The damage dealt is equal to Isaac's current tear damage plus 10% of the enemy's max health, Every time this item deals damage, it has a 15% chance to drop 1/2 red hearts, REPENTANCE - Sharp Straw is now only able to generate half red hearts (previously, it generated half soul hearts if the player had no heart containers), A razor blade orbital that deals contact damage and applies the bleeding status effect to enemies and bosses, which will cause them to take damage every 5 seconds, The contact damage dealt by Mom's Razor is based on how quickly an enemy is moving (faster enemies take more damage), Its speed is not affected by the Guardian Angel item, An eye orbital that shoots tears that deal 3.5 damage and deals 2 contact damage per tick to enemies, The damage dealt by this orbital does not scale with damage upgrades, REPENTANCE - Bloodshot Eye now blocks enemy shots, has increased shot speed and rate of fire, and now only shoots when lined up with enemies, When used, spawns a charmed random white delirium version of a boss, that will fight for you and kill other enemies for the rest of the current room, Possible bosses spawned include most bosses in the game, Some bosses' effects can harm Isaac. by doing a victory lap), UNLOCK: Unlock this item by beating Mom's Heart on Hard Mode with Apollyon, *, grey, gray, brown, orange, steam, coffee, tea, drink, cup, When used, Compost doubles up the current number of blue flies and spiders you have, When picked up, Compost will also destroy every consumable on the ground in the current room and turn each of them into a blue fly or blue spider, If you have no pickups on the ground in the current room and no other flies or spiders, Compost will spawn 1 blue fly or blue spider, When used, this item will distort all the sprites and music, rotating graphics 90 degrees and translating them diagonally up/left, while leaving the hitbox in the same place. Bosses Challenges Does not apply Monstro's Lung's tears down. Character Appearance The Binding of Isaac Rebirth and Afterbirth has been updated to version 1.15 and 1.05 today. Both the box and trinket are consumed when this happens, UNLOCK: Unlock this trinket by defeating Isaac, ?? 3 or more keys = 100% chance. These ticks occur every 1/15th of a second (once every 4 frames). Boosts speed, range, shot speed, tears and damage if they are above their base values by roughly +20%, Affects stat bonuses from passive items, trinkets that are absorbed or in a second trinket slot, and permanent bonuses given by items such as Void, UNLOCK: Unlock this trinket by getting a 5-win streak in daily challenges (must have a score of above 0 on the score screen), While held, gives the Skatole effect only in certain rooms, which will turn hostile flies to neutral and stop others from shooting, Attack, Dart and Ring Flies turn into neutral Black Flies and Pooters and Fat Flies will no longer fire at you, Items and trinkets which generate blue flies and spiders will have double the effect, causing twice as many to spawn, *, grey, gray, green, arrow, flower, plant, Some tears will randomly become a black tooth, that deal double your normal tear damage and can poison enemies, Tears become spectral and travel in a huge spiral pattern, Every time you take damage you have a very small chance to gain a Tonsil familiar, which follows you and blocks enemy projectiles, This effect can happen twice before the Tonsil trinket is destroyed, Your tears have a random chance to become booger tears, Booger tears stick on to enemies and deal periodic poison damage until they die or 60 seconds passes. Spawns a Sumptorium blood clot Familiar on the ground next to Isaac. * item room, treasure room, item room pool, round, circle, white, REPENTANCE - Homing tears now target enemies much more reliably, * item room, treasure room, item room pool, grey, gray, bent, x1.5 times Damage Multiplier (Does not stack with the Magic Mushroom multiplier), Cricket's Head used to be known as Max's Head in the original game and was renamed for Rebirth, * crickets head, cricket head, item room, treasure room, item room pool, golden chest pool, gold chest pool, cat, dead, brown, pink, * item room, treasure room, item room pool, broken, mirror, cracked, grey, gray, silver, Gives you a very high tear rate in exchange for a big range down, * item room, treasure room, item room pool, mm sweet lemonade, urine, yellow, tear, drop, x1.5 times Damage Multiplier if you also have Book of Belial (Does not stack with Magic Mushroom or Cricket's Head multipliers), * item room, treasure room, item room pool, crown, thorns, brown, hat, A familiar which follows Isaac and shoots normal tears which do 3.5 damage, REPENTANCE - Brother Bobby now has an increased rate of fire, * item room, treasure room, item room pool, devil pool, devil room pool, devil deal, purple, blue, dead, baby, A lot of fly enemies are no longer aggressive towards Isaac, Attack Fly, Dart Fly, Eternal Fly, and Ring Fly are transformed into a neutral black fly, Boom Fly, Red Boom Fly, Drowned Boom Fly move slower, but still deal contact damage, Moter, Level 2 Fly, Full Fly, Pooter, and Super Pooter move slower and deal no contact damage, Can only be obtained from the shell game in the arcade. 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